青阳县山区流行性出血热疫源地调查

Investigation on Epidemic Focus of EHF in the Mountain Areas of Qingyang County

目的 探讨青阳县山区流行性出血热疫源地概况。方法 分析基础资料 ,同时调查鼠密度和鼠种构成 ,用IFA法检测健康人群隐性感染情况和鼠血EHF·VIg、鼠肺组织中EHF·V抗原以及EHF·V分离。结果 山区野外鼠密度为 1 3 .6 % ,居民区鼠密度为 1 0 .7% ,山顶野外中华姬鼠为优势种 ,居民区黄胸鼠为优势种 ;山脚野外黑线姬鼠为绝对优势种 ,居民区褐家鼠为优势种。健康人群隐性感染率为 3 .7%。山顶野外鼠带毒率为 2 .3 % ,总感染率为 9.3 % ,山脚野外鼠带毒率为 7.4% ,总感染率为 7.4% ,居民区鼠带毒率为 6 .3 % ,总感染率为 8.3 % ,并在大足鼠阳性鼠肺中分离出一株EHF·V。结论 通过本次调查证实青阳县山区存在EHF疫源地 ,黑线姬鼠、社鼠。

Objective In order to understand epidemic focus of EHF in the mountain areas of Qingyang county, basic data were analyzed. Methods The density and proportion of mice were investigated. Inapparent infection of natural population and mice blood EHF V-IgG, mice lung EHF V-Ag were detected with IFA. EHF V was isolated from mice lung. Results The density of mice at mountain areas was 13.6%. 10.7% at inhabitant areas. Rattus niniventer was the dominant species in the field on the top area of the mountains. R. flavipectus was the dominant species in inhabitant area on the top of the mountains. A. agrarius was the dominant species in the field on the foot of the mountains and R. norvegicus was the dominant species at inhabitant areas on the foot of the mountains. The rate of inapparent infection of natural population was 3.7%. EHF V carried rate of the mice from the top of the mountains was 2.3%. Total infection rate was 9.3%. The carried rate of mice from the foot of the mountains was 7.4%. Total infection rate was the same as the carried rate. EHF V carried rate of mice from inhabitant areas was 6.3%. Total infection rate was 8.3%. A strain of EHF V was isolated from the lung of R. nitidus. Conclisions It was proved that epidemic focus of EHF in the mountain areas of Qingyang county were still exist and A. agrarius, Rattus niniventer and R. norvegicus were the main source of infection.