期刊文献+

国产盐酸阿扎司琼注射液止吐疗效观察 被引量:8

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摘要 呕吐是癌症患者在化疗过程中常出现的药物不良反应之一。由日本吉富制药株式社研制开发、1997年经国家卫生部药政局批准进口的盐酸阿扎司琼注射液(azasctron hydrochloride injection)(注册号:X970086,商品名为Serotone,苏罗同)对5-HT受体具有高选择性及强有力的阻断作用,能有效地控制恶心、哎吐,且不产生锥体外系症状[1,2],但该药的价格比较昂贵,难以作为临床预防性用药.
出处 《第二军医大学学报》 CAS CSCD 北大核心 2002年第4期377-377,416,共2页 Academic Journal of Second Military Medical University
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  • 1[1]Beppr T,Ogawa W,Yamanaka T.Clincal evalutions of azasetron hydrodhliride: anew selective 5-HT3 receptor antagonest antiemetic profile and plasma concentration in transcatheter arterial chemoembolization using cDDP for unresectable hepatocellular carcinoma[J].Gan To Kagaku Ryoho,1998,25(8):1191-1202.
  • 2[2]Kimura E,Niimi S,Watanabe A,et al.Clinical effect of tow azasetron treatment methods against nausea and vomiting induced by anticancer drugs including cDDP[J].Gan To Kagaku Ryoho,1997,24(7):855-859.
  • 3[3]Soukop M.A comparison of low dose levels of granisetron in patients receiving high dose cisplatin[J].Eur J Cancer,1990,26(2):15-19.

同被引文献26

  • 1吴孟超,程树群.肝癌微创外科治疗的现状和展望[J].中国微创外科杂志,2005,5(2):85-87. 被引量:37
  • 2戴载深,何永传.不同止吐药预防曲马多静脉镇痛后恶心呕吐的疗效观察[J].临床麻醉学杂志,2005,21(9):609-610. 被引量:16
  • 3谢龙,张丽莹.盐酸阿扎司琼注射液预防化疗所致呕吐的临床观察[J].抗感染药学,2005,2(4):168-169. 被引量:4
  • 4沈杨,游建华,赵慧瑾,钱樱,李军民,沈志祥,黄小飞.阿扎司琼和蒽丹西酮预防急性白血病化疗相关恶心和呕吐的单中心回顾性研究[J].上海医学,2006,29(3):150-152. 被引量:2
  • 5Ayuhara H,Takayanagi R,Okuyama K,et al.Receptor occupancy theory-based analysis of interindividual differences in antiemetic effects of 5-HT3 receptor antagonists [J].Int J Clin Oncol,2009,14(6):518-524.
  • 6Lagraize S C,Guo W,Yang K,et al.Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla [J].Neuroscience,2010,171(4):1341-1356.
  • 7Beppu T, Ogawa M, Yamanaka T, et, al. Clinical evaluation of Azasetron Hydrochloride:a new selective 5-HT3 receptor antagonist--antiemetic profile and plasma concentration in transcatheter arterial chemoembolization using CDDP for unresectable hepatocellular carcinoma[ J ].Can To Kagaku Ryoho, 1998,25 (8) :1197-1202.
  • 8Kimura E, Nilmi S, Watanabe A, et, al. Clinical effect of two azasetmn treatment methods against nausea and vomiting inducedby anticancer drugs including CDDP[ J ]. Gan To Kagaku Ryoho,1997,24(7) : 855-859.
  • 9Kimura E, Niimi S, Watanabe A, et, al. Study on clinical effect of a continuous intravenous infusion of azasetron against nausea and vomiting induced by anticancer drugs including CDDP[J]. Can To Kagalm Ryoho,1996,2,3(4) : 477-481.
  • 10Haga K, Kato A, Matsumoto Y, et al. Ten binging of azasetron hydrochioride for various of receptors. JPN Pharmacol Ther, 1999,27(9) :31-35.

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