黏膜层加固硬化疗法对食管曲张静脉闭塞再通的疗效

Mucosal strengthening and hardening in treatment of closed varicosity veins of esophagus

目的：观察黏膜层加固硬化疗法对闭塞的食管曲张静脉再通的预防作用。方法：对136例经过硬化、结扎治疗使食管静脉曲张闭塞和消失的患者进行黏膜层加固硬化治疗，观察其疗效，并通过内镜及内镜超声观察曲张静脉变化。对128例相同病情的患者行非加固治疗作对照组。随访1～13年。结果：加固治疗组无食管静脉曲张复发及再出血，而对照组有25例（19．5％）出现孤立状或条状曲张静脉伴有红色征，21例（16．4％）细小静脉变粗、局部黏膜充血明显，6例（4．7％）再出血，两组间有显著差异（P＜0．05）。结论：黏膜层加固硬化疗法对已闭塞的食管曲张静脉有防止曲张静脉复发和再出血的确切疗效。

Objective:To investigate the effects of mucosal strengthening treatment on preventing recurrence of closedvarices. Methods: In 264 patients with esophageal varices obliteration by banding ligation and sclerotherapy, of 136 patientswere gone on to treat with strengthening mucosa, and 128 patients without strengthening treatment. All patients had beenobserved out of hospital for 1-13 years. Results: There were no recurrence and rebleeding of esophageal varices in the groupwith strengthening treament. But in the group without strengthening treatment, 25 patients (19. 5%) had isolated or strip-like varices with red colour signI small veins grew thick and part of mucosa appeared clear hyperaemia in 21 patients(16.4% ); 6 patients (4.7% ) rebleeded. There were significant differences between two groups (P<0.05). Conclusion:Treatment with strengthening mucosa definitly had good strong effects on esophageal varices obliteration, which could pre-vent recurrence and rebleeding of esophageal varices.