摘要
目的 探讨冠心病 (CHD) ,病情程度与白细胞介素 -6(IL -6)及甘油三酯 ;高密度脂蛋白胆固醇 (TG HDL -C)比值的关系。方法 测定 73例CHD患者血浆IL -6浓度 ,TG浓度 ,HDL -C浓度及TG HDL -C比值 ,并与对照组 (健康者 3 0例 )相比较 ,分析IL -6及TG HDL -C比值的临床意义。结果 IL -6浓度及TG HDL -C比值在对照组 ,稳定型心绞痛 (SAP) ,不稳定型心绞痛 (UASP)组分别为 :98± 41ng L ,1.87± 0 .41;2 82± 13 6ng l;3 .2 6± 0 .81;5 12± 2 5 9ng l,3 .66± 1.0 2 ;SAP组及UASP组明显高于对照组 (NC)分别 (P <0 .0 1,P <0 .0 5 )。结论 :IL -6及TG HDL-C比值在临床评价CHD病情程度具有一定的指导意义。
AIM: To study the relation of the plasma IL-6 and TG/HDL-C ratro to the severity of coronary heart disease(CHD).Methods:The plasma IL-6 concertration.TG concentration,HDL-C concentration and TG/HDL-C ratto were rested in 73 patients,and were compared with those of the normal control group(n=30),in order to analyse the clinical significance of IL-6 and TG/HDL-C ratio.Results:The plasma IL-C cocentration and TG/HDL-C ratio were 98±41ngh and 1.87±0.41,282±136ngh and 3.26±0.81,512±259ngh and 3.6±1.02,respectively,for the normal control group,the stable angin group and the unstable angina group.The two indices in the stable and the unstable angina groups were significantly higher than those of the normal control group(respectively p<0.01,p<0.05).Conclusion:IL-6 and TG/HDL-C ratio serve predicting indices for clinical evaluation of severity in CHD.
出处
《海南医学》
CAS
2002年第4期4-5,共2页
Hainan Medical Journal