15例脊髓空洞症放射治疗疗效分析

The Role of Radiotherapy for the Treatment of Syringomyelia in 15 Cases

[目的]探讨放射治疗对脊髓空洞症的治疗作用。[方法]回顾性分析1993年3月至2001年3月该院共收治的15例脊髓空洞症患者的疗效 ,采用钴60或6MVX线或电子束照射 ,剂量21.6Gy,分次量为1.2Gy/次 ,每周5次。[结果]完全恢复 (CR)2例 ,好转(PR)8例 ,有效率66.7% ,稳定 (SD)3例 ,进展 (PD)2例。全组均无明显放疗反应。[结论]放射治疗是脊髓空洞症的一种重要的治疗方法 。

To evaluate the role of radiotherapy for the treatment of syringomyelia.From March 1993 to March 2001, 15 patients with syringomyelia were retrospectively analyzed. All patients were treated by radiotherapy (Cobalt-60, 6MV photon or electron beam). The total radiation dose was 21.6Gy with 18 fractions of 1.2Gy.A complete clinical response was noted in two patients and a partial response in eight patients, which represents a 66.7% overall response rate. Three patients had stable diseases, and two patients had progressive disease. No severe toxicity was observed in the series.[Conclusion] Radiotherapy is one of the effective treatments for patients with syringomyelia, but it is less effective for those combined with Chiari aberrant or with longer course.