内科危重症患者血清ACE活性变化的研究

Serum angiotensin-converting enzyme in critically ill patients

地66例内科危重症患进行血清血管紧张素转换酶（ACE）测定，结果显示、哮喘、呼吸衰竭、脑卒澡ACE均值低于正常对照组（P<0.01），肺部感染高于正常组（p<0.05）；ACE与多器官功能衰竭数量呈负相关，死亡组ACE活性均值低于存活组；求出27例患进行PaO2与ACE相关回归方程，r=0.984,P<0.01，证明PaO2变化与ACE活性均值呈正相关。

The serum angiotensin-converting enzyme (SACE) was quantified in 66 critically ill patients. SACE was lower in parients with asthma, respiratory failure and cerebral stroke but higher than normals in patients with pulmonary infection (p<0.01, p<0.05). with multiple organ failure, SACE decreases as the failure progressing. The survirors had higher SACE than the dead ones. Serum SACE was found to be in positive correlation with PaO2 (r = 0.984, p<0.01).