甘草与黄芩免疫调节作用的体外观察

Observation on In-vitro Immunoregulation of Glycyrrhiza and Baicalensis

本文观察了甘草与黄芩对人外周血淋巴细胞产生白细胞介素2(IL2)及形成抗体分泌细胞能力的调节作用,结果证明炙甘草与黄芩有增强 IL2产生的作用,而对抗体分泌细胞的形成则无明显影响。说明炙甘草与黄芩在机体的免疫应答过程中可能有选择地增强细胞免疫的作用,对体液免疫作用则不明显。生甘草在上述两项体外免疫应答试验中均未见有明显作用。

Described here were the effect of Glycyrrhiza and Bicalensis on IL2 productionof peripheral blood lymphocyte induced by PHA,and the formation of antibody-se-creting cell of peripheral blood lymphocyte induced by PWM.The results showed thatboth the roasted Glycyrrhiza and the Baicalensis elevated the level of IL2 productionsignificantly as compared to the control group,but neither of them had significanteffect on the antibody-secreting cell formation.It Was suggested that these two her-bal medicines might selectively up-regulate the cellmediated immune response rather than the humoral immune response.Interestingly,using these two parameters,theraw Glycyrrhiza showed no effect at all on the immune response.