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生理及病理时血管顺应性、弹性模量改变的初步观察 被引量:2

Preliminary Observation on Normal and Pathologic Changes of Arterial Compliance and Elastic Modulus
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摘要 作者测定了不同年龄组正常人和动脉硬化闭塞病患者的动脉顺应性、弹性模量,颈一股和肱—桡脉波速度。实验表明,零压顺应性(Co)随年龄增长而降低,弹性模量(E_1)随年龄增加而逐渐增大,能较好反映血管的生理性改变。动脉硬化闭塞症组 Co、E_1 与同年龄正常组比较差异非常显著(P<0.001)并与动脉硬化损伤程度有关。结果表明,本法对了解血管的弹性特性生理及病理改变是十分有价值的方法,灵敏度高,特异性强。 Determinations of arterial compliance and elastic modulus have been shown us- eful method in studying pathophysiologic mechanisms.Arterial compliance,elasticmodulus,carotid-femoral and brachioradial pulse wave velocities were measured in67 subjects:55 normal subjects and 12 patients with artericscleotic obliteration(ASO).The results showed that the Co of 12 patients with ASO was much lowerthan that of 35 normal subjects in the same age(P<0.001).The E increased gra-dually with age and worsening degree of arteriosclerosis.The results showed thatthis method Would be valuable in clinical application and hemodynamic study.Thismethod is very sensitive and specific.
出处 《天津医药》 CAS 1991年第12期710-713,共4页 Tianjin Medical Journal
关键词 动脉顺应性 动脉硬化 诊断 arterial compliance elastic modulus pulse wave velocity arteriosclerosis
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