摘要
为探讨153 Sm -EDTMP(153 钐 -乙二胺四亚甲基膦酸 )与云克 (99Tc -MDP ,即99锝 -亚甲基二膦酸盐 )联合治疗转移性骨肿瘤疼痛的临床价值。对 2 10例癌骨转移患者分别用153 Sm -EDTMP单独治疗或与云克联合治疗 ,观察其疗效。结果显示 ,153 Sm -EDTMP单独治疗组 ,止痛有效率为 83.7% ,转移灶消失或缩小的总有效率为 2 1.6% ;153 Sm -EDTMP与云克静脉滴注联合治疗组 ,止痛有效率为 94 .7% ,转移灶消失或缩小的总有效率为 35 .1%。后者明显高于单独治疗组。表明153 Sm -EDTMP联合云克静脉滴注对恶性肿瘤多发性骨转移所致疼痛有明显疗效 ,且安全无副作用。联合治疗组疗效优于单独治疗组。
To evaluate the clinical value of combined 153 Sm-EDTMP and Yunke therapy in metastatic bony pain. 210 patients with metastatic bony pain were treated using 153 Sm-EDTMP or combined with Yunke. The effect of treatment were observed. The total pain relief rate in single 153 Sm-EDTMP group was 83.7%, whereas in combined 153 Sm-EDTMP with Yunke group was 94.7%. The latter was markedly higher than the former. The clinical value of combined 153 Sm-EDTMP and Yunke therapy group in relief of metastatic bony pain is obvious. And it was safe and no significant adverse reaction was observed. The pain relief effect of combined 153 Sm-EDTMP and Yunke therapy is better than the single 153 Sm-EDTMP therapy.
出处
《核技术》
CAS
CSCD
北大核心
2002年第5期349-352,共4页
Nuclear Techniques
