泌尿外科病房大肠埃希菌流行病学调查

Epidemiological study on Nosocomial Escherichia Coli Infection in Department of Urological Surgery

目的 探讨泌尿外科病区大肠埃希菌的流行病学分布及其耐药性。方法 采用病房现场采样 ,了解大肠埃希菌的分布。结果 采集的 176 5份样本共检出大肠埃希菌 86株 ,平均检出率为 4 .9%。其中 ,产 ESBL s菌为 35株。大肠埃希菌耐药率低的抗生素是亚胺培南、阿米卡星、哌拉西林 /三唑巴坦 ,<15 % ,产 ESBL s菌对二、三代头孢菌素的耐药性较高 ,>5 0 %。结论 大肠埃希菌是泌尿外科病区的常见病原菌 ,治疗其感染时 ,应根据药敏结果及患者病情选用氨基糖苷类、β-内酰胺类抗生素

Objective To discuss the epidemiology and drug resistance of Escherichia Coli in department of urological surgery.Method Distribution of Escherichia Coli was learned by spot sampling.Results 86 strains of EC was found in the overall 1765 samples(4.9%) with 35 strains of ESBLs producing bacteria.EC showed low drug resistance to imipenem,amikacin and piperacillin/tazobactam (<15%),and ESBLs producing bacteria showed high drug resistance to the second and the third generation of cefa like antibodies(>50%).Conclusion EC was the familiar pathogen in urological surgery ward and doctors should choose aminoglycosides, β lactams/β lactamase inhibitors and imipenem to treat patients accordingto results of drug resistance tests.