季铵盐催化合成7,7-二氯双环[4.1.0]庚烷

Catalytic synthesis of 7,7-dichlorodicyclo[4.1.0]heptane catalyzed by quaternary ammonium salt A-1

研究了季铵盐 A-1催化二氯卡宾与环己烯的加成反应 ,考察了不同相转移催化剂的催化活性、反应温度、催化剂用量、反应时间对产物 7,7-二氯双环 [4.1 .0 ]庚烷收率的影响。在优化反应条件 (即反应温度为 5 0℃ ,反应时间为 5 h)下 ,以季铵盐 A-1为相转移催化剂 ,产率可达 94.0 %。实验证明 ,季铵盐 A-1的催化活性要优于其他短碳链的季铵盐和聚乙二醇 ,并且在分离过程中不乳化 。

The catalytic synthesis of 7,7 dichlorodicyclo heptane(DCDCH)with phase transfer catalyst (PTC), quaternary ammonium salt A 1,was reported The effects of different factors,such as PTC amount,PTC activity,reaction temperature and reaction time,on the yield of DCDCH were investigated Under the optimal reaction conditions (reaction time 5 h,temperature 50℃ with A 1 as PTC),the yield of DCDCH was 94 0% The experiment results show that the catalytic activity of A 1 was better than that of some other short chain alkyl quaternary ammonium salts and polyethylene glycol. A 1 was not emulsive in separation and purification,which makes the separation and parification earier and raises the product yield