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热休克蛋白与肿瘤免疫治疗 被引量:4

Heat Shock Protein and Cancer Immunotherapy
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摘要 热休克蛋白 (HSP)与肿瘤免疫的关系是近年来的研究热点之一。HSP肽复合物携带有多个T细胞表位 ,通过与APC细胞上的受体结合而内化 ,经MHCⅠ类途径诱导特异性抗肿瘤免疫应答。HSP与抗原的融合蛋白也能激活抗原特异性的CTL反应。HSP肽复合物和HSP融合蛋白可用于肿瘤的特异性免疫治疗 ,临床应用前景广阔。
出处 《中国肿瘤生物治疗杂志》 CAS CSCD 2002年第1期65-67,共3页 Chinese Journal of Cancer Biotherapy
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参考文献21

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同被引文献38

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