摘要
目的 探讨患者治疗前血清鳞状上皮细胞癌抗原（ＳＣＣ－Ａｇ）与宫颈癌生物学行为的相关性及其临床意义。方法 采用酶免疫微粒子（ＭＥＩＡ）法检测８５例宫颈癌患者治疗前血清ＳＣＣ－Ａｇ值，分析ＳＣＣ－Ａｇ检测值与宫颈癌临床病理特征之间的关系。结果 宫颈癌患者治疗前血清ＳＣＣ－Ａｇ升高与临床分期、肿瘤浸润肌层深度、淋巴结转移呈正相关（Ｐ＜０．０５），肿瘤生长于宫颈管者较宫颈外口者 ＳＣＣ－Ａｇ阳性率低，而血清 ＳＣＣ－Ａｇ升高与肿瘤组织分化程度、组织学类型、生长类型无关（Ｐ＞０．０５）。结论 治疗前血清 ＳＣＣ－Ａｇ值对估计宫颈癌的生物学行为有重要的临床参考价值。
Objective To investigate the clinical significance and the relationship between the pre - treatment serum squamous cell carcinoma antigen (SCC - Ag) levels and the biological characteristics in patients with cervical cancer. Methods The pre - treatment sera from 85 patients with cervical carcinoma from 1995 to 1996 were analyzed for the SCC - Ag levels by MEIA; and the correlation between the SCC - Ag levels and the clinicopathologic characteristics were also detected. Results Significant correlations were found between the SCC - Ag levels of the pre - treatment serum SCC - Ag and clinical stage, depth of invasion, the lymph nodes status (P < 0.05),patients with cervical tube cancer had lower SCC - Ag positive rate than patients with extermal uteruses cancer, no relation was found between the SCC - Ag levels of the pre -treatment serum SCC - Ag and the grade, pathologic classification, style of growth (P> 0.05) .Conclusion Pre treatment SCC - Ag levels plays an important role in evaluating the biological characteristics in patients with cervical cancer.
出处
《中国实验诊断学》
2002年第2期69-71,共3页
Chinese Journal of Laboratory Diagnosis
