新生儿TORCH感染的临床研究

The clinical study on the neonatal TORCH infection

目的 了解巨细胞病毒（ＣＭＶ），风疹病毒（ＲＶ），弓形虫（ＴＯＸ），单纯疤疹病毒（ＨＳＶ）和其他病原体（Ｏｔｈ－ｅｒｓ）（总称ＴＯＲＣＨ）在住院新生儿中的感染情况。方法 应用ＥＬＩＳＡ法检测６５例住院新生儿血清ＣＭＶ，ＴＯＸ，ＲＶ和ＨＳＶ２抗体。结果 ６５例住院新生儿中 ＣＭＶ阳性 １４例，ＴＯＸ阳性 ８例，ＨＳＶ２阳性 ５例，ＲＶ阳性 ３例。感染率分别占同期住院新生儿的２１．５４％，１２．３１％，７．６９％，４．６２％。ＴＯＲＣＨ总的感染率为２７．６９％（１８／６５）。结论 我院住院新生儿中ＴＯＲＣＨ感染情况较为普遍，其中以ＣＭＶ为主，ＴＯＸ感染次之。因此在新生儿疾病的诊治过程中，应在临床诊断的基础上，进一步查找病因，及早做ＴＯＲＣＨ－ＩｇＭ检测，以便更有什对性地指导治疗，判断预后，减少远期并发症的发生。

To study the conditions of 'FOX, RV, CMV, HSV infection(that is TORCH infection) among the neonates in our hospital. Methods A total of 65 neonates in our hospital were given serum TORCH-IgM tests with EIISA method. Results There were altogether 18 patients with positive TORCH-IgM with in 65 neonates in hospital. Among them there were 14 with positive CMV-IgM,8 with TOX-IgM,5 with positive HSV2-IgM,and 3 with positive RV-IgM. The infection rate were 21.54%,12.31% ,7.69% ,4.62% respectively in the neonates in hospital. The total infection rate of TORCH is 27.69%(18/65). Conclusions TORCH infection is very common in neonates in our hospital. CMV infection was the commonest, and the TOX infection came next.