期刊文献+

人颈动脉窦内流动分离区的研究 被引量:5

STUDY ON THE FLOW SEPARATION IN HUMAN CAROTID BI FURCATION
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摘要 关于人颈动脉粥样硬化病的病理解剖报告指出,在窦内侧或内外侧同时发生内膜增生和粥样斑块的病例很多见。用血流动力学低切应力因子相关理论,在传统的Y型AHCB模型中无法解释这种现象。本文在音叉型AHCB修正模型中,用可视化技术显示颈动脉窦内定常三维流场,用激光测速技术测量颈动脉窦内膜增生部位的速度剖面,发现除窦外侧分离区外还存在窦内侧分离区,使临床上观察到的粥样斑块分布现象得到合理解释,并证明音叉型AHCB模型是对传统模型的明显改进。 The anatomy reports indicated that atherosclerotic lesions were located on the inner wall,or both inner and out-er walls of the sinus of the carotid bifurcation in the many cases.This phenomenon was not explained by the hypothesis about the low wall shear stress in the traditional Y-AHCB model.In this paper,in the modified model of″average human carotid bi furcation(AHCB)″the three-dimension field in carotid sinus under steady flow conditions was studied using flow visualization techniques and laser-Doppler anemometer(LDA).The effects of the shape of branches on the flow separation and were observed.A new separation zone along inner wall of sinus was found.It can be used to explain plaque distribution on the inner wall of sinus.The modified model was proved to be a more rational model for hemodynamics and atheosclerosis study in human carotid bifurcation.
出处 《医用生物力学》 EI CAS CSCD 2002年第1期28-32,共5页 Journal of Medical Biomechanics
关键词 血流动力学 颈动脉分叉 流动可视化 激光测速 颈动脉窦 颈动脉粥样硬化 hemodynamics,human carotid bifurcation,flow visualization,LDA
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  • 1王克强,杨俊华,吴国强,于彦铮,肖子顺,黄德桥,施建英.腹主动脉分叉处粥样斑块分布及其意义[J].上海医科大学学报,1989,16(6):427-430. 被引量:6
  • 2中国解剖学会调查委员会.中国人体质调查[M].上海:上海科学技术出版社,1990..
  • 3汪国伟,上海医科大学学报,1991年,18卷,3期,237页
  • 4Ku D N,Atherosclerosis,1983年,3卷,31页

共引文献17

同被引文献43

  • 1刘珊,丁祖荣.弯曲圆管入口段定常流动的三维数值模拟[J].医用生物力学,2004,19(2):65-68. 被引量:4
  • 2汪君红,丁祖荣.无创伤性血流测量[J].医用生物力学,2003,18(4):244-249. 被引量:3
  • 3薛蕴菁,高培毅,林燕,代成波.颈动脉分叉血液动力状态的计算流体力学初步研究[J].中华放射学杂志,2006,40(6):638-641. 被引量:16
  • 4ZHAO S Z,XU XY,HUGHES A D et al.Blood flow and vessel mechanics in a physiologically realistic model of a human carotid arterial bifurcation[J].Journal of Biomechanics,2000,33:975-984.
  • 5ZHAO S Z,ARIFF B,LONG Q,et al.Inter-individual variations in wall shear stress and mechanical stress distributions at the carotid artery bifurcation of healthy humans[J].2002,35(10):1367-1377.
  • 6YOUNIS H F,Kaazempur-Mofrad M R,CHAN R C,et al.Hemodynamics and wall mechanics in human carotid bifurcation and its consequences for atherogenesis:investigationof inter-individual variation[J].Biomechanics and Modeling in Mechanobiology,2004,3(1):17-32.
  • 7MOORE J A,STEINMAN D A,HOLDSWORTH D W,et al.Accuracy of computational hemodynamics in complex arterial geometries reconstructed from magnetic resonance imaging[J].A nnals of Biomedical Engineering,1999,27:32-41.
  • 8JUAN R C,RAINALD L.From medical images to anatomically accurate finite element grids[J].Int.J.Numer.Meth.Engng,2001,51:98521008.
  • 9JOHNSTON B M,JOHNSTON P R,CORNEY S,et al.Non-Newtonian blood flow in human right coronary arteries:Transient simulations[J].Journal of Biomechanics,2006,39:1116-1128.
  • 10RAYZ V L.,BERGER S A.,SALONER D.Transitional flows in arterial fluid dynamics.Comput.Methods Appl.Mech.Engrg.2007,196:3043-3048.

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