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微血管密度、微血管面积及nm23表达在大肠癌淋巴结转移中的作用及意义

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摘要 应用免疫组化S -P法 ,检测nm2 3在伴淋巴结转移大肠癌组 (89例 )和不伴淋巴结转移大肠癌组 (12 7例 )肿瘤组织中的表达 ,并同时测定各组肿瘤的微血管密度及微血管面积。结果 ,伴淋巴结转移大肠癌组中nm2 3高表达数量 (4 3/ 89)比不伴淋巴结转移大肠癌组 (118/ 12 7)明显减低 (P <0 .0 1) ;伴淋巴结转移大肠癌组微血管密度为 5 0 .8± 2 1.8、微血管面积为 2 382 8.0± 9817.3;不伴淋巴结转移大肠癌组微血管密度为 34 .1± 19.3,微血管面积为 10 0 5 2 .9± 6 0 38.7,二组有显著性差别 (P <0 .0 1)。
作者 张熔熔
出处 《苏州大学学报(医学版)》 CAS 2002年第2期184-184,187,共2页 Suzhou University Journal of Medical Science
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参考文献5

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