Therapeutic effect of irregular dividing radiotherapy on pain due to metastatic tumors of mammary cancer

Objective To investigate therapeutic effect of rapidly divided radiotherapy in the management of pain due to bone metastases in mammary cancer. Method 20 patients among 33 received rapidly divided radiotherapy in 25 lesions, DTU 5CTY a time, 2～3 times a week, total dose was 15～30 Gy. 13 patients (22 lesions ) received routine dividing radiotherapy, DT 4～5 Gy each time, 5 times a week, total dose was 40～60 Gy. Result In rapidly divided group, total analgesic rate was 95.0% (19/20). In routine dividing group, total analgesic rate was 69.3%. There was no significant difference between the 2 groups (P >0.05). Pain was controlled in 84% of lesions in rapidly divided group 2 week after radiotherapy. Analgesic rate of DT 20～30 Gy went up to 45.5%. Differences between 2 groups were significant statistically (P< 0.01).Conclusion Rapidly divided radiotherapy is rapid and reliable in managing pain. Patients can endure its toxicological and adverse reactions . It’s therapeutic effect is comparable with that of routine divided radiotherapy.