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Investigation on the change of nitric oxide synthetase positive neurons in hippocampus CA1 area of rats with hyperglycemia

Investigation on the change of nitric oxide synthetase positive neurons in hippocampus CA1 area of rats with hyperglycemia
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摘要 Objective To observe the expression of nitric oxide syhthetase(NOS) in hippocampus CA1 neurons with hyperglycemia.Method NADPH d histochemical method was used.Rcsults NOS positive neurons expressed in hippocampus CA1 and nomal neurons of 6 weeks old rats with hyperglycemia(DM) and normal rats(NC).There was significant difference in neurons between DM group and control group.Conclusion NOS positive neurons decrease in hippocampus CA1 of rats with hyperglycemia. Objective To observe the expression of nitric oxide syhthetase(NOS) in hippocampus CA1 neurons with hyperglycemia.Method NADPH d histochemical method was used.Rcsults NOS positive neurons expressed in hippocampus CA1 and nomal neurons of 6 weeks old rats with hyperglycemia(DM) and normal rats(NC).There was significant difference in neurons between DM group and control group.Conclusion NOS positive neurons decrease in hippocampus CA1 of rats with hyperglycemia.
出处 《中国临床康复》 CSCD 2002年第8期1232-1232,共1页 Chinese Journal of Clinical Rehabilitation
关键词 高血糖 海马CA1区 一氧化氮合成酶 NOS 阳性神经元 hyperglycemia nitric oxide synthetase hippocampus rat
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参考文献3

  • 1VINCENTSR,KIMURAH.Histochemicalmappingofnitricoxidesynthaseintheratbrain犤J犦[].Neuroscience.1992
  • 2SHIBUKIK,OKADAD.Endogenousnitricoxidereleaserequiredforlong-termsymapticdepressioninthecerebellum犤J犦[].Nature.1991
  • 3GILBALDIM.Whatisnitricoxideandwhyaresomanypeoplestudyingit?犤J犦[].JClinPharmacol.1993

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