2,6-O-二戊基-3-O-乙酰基-β-环糊精的制备及其在手性化合物色谱分离中的应用

Preparation of 2,6-O-di-pentyl-3-O-acety1-β-Cyclodextrin and used in Chromatography Separation of Enantiomers

合成了一种新的烷基化和乙酰基化的 β 环糊精 ,将其用作固定相涂渍到弹性石英毛细管柱上 ,考察了手性毛细管柱的色谱性能 ,对一些对映体进行了手性拆分。实验表明 。

A new alkylated and acetylated β-cyclodextrin has been synthesized and used as chiral stationary phase of gas chromatography,a fused silica capillary column was prepared with this derivative.The performance of the column was investigated and a series of enantiomers were separated.The experimental results indicate that chiral stationary phase is of excellent chromatographic properties and strong enantioselectivity.