急性创伤对组织细胞内cAMP、cGMP及DNA水平的影响

Effect of Acute Trauma on the Levels of Intracellular cAMP, cGMP and DNA

本试验以杂种狗为试验对象,通过检测内分泌与代谢器官组织细胞内环磷酸腺苷、环磷酸鸟苷及DNA水平的变化,探讨创伤对神经内分泌与代谢器官,内分泌激素之间及其对代谢的影响。从细胞内环核苷酸水平的变化,阐述了创伤后许多神经内分泌与主要代谢器官都以α-肾上腺素受体占优势的特征以及高血糖产生的来源。

In this experiment, we used the heterogeneous dogs to study the effect of trauma on the neuro-endocrine and metabolic organs and the effects of hormones on metabolic by determination of the levels of intracellular cAMP, cGMP and DNA. From the changes in intracellular cyclic nucleotides, we learned that many neuro-endocrine organs and the main metabolic organs are characteristic of predominance in a-adrenoreceptor after trauma, thereby leading to high blood sugar.