尿路清制剂对几种常见泌尿生殖道病原体的抑制试验

Observation on Antibacterial Activity of Niaoluqing Liquid Against Some Common Pathogenic Germs in Urinary and Genital System.

目的:探讨中药尿路清对几种常见泌尿生殖道病原体的抑制作用,为中医药治疗此类疾病提供中药药理学依据。方法:采用液体试管法和微量稀释法测定尿路清对某些病原体的体外抑制效应。结果:尿路清对金黄色葡萄球菌、乙型溶血性链球菌、丙型链球菌、卡他球菌、大肠杆菌、绿脓杆菌、白色念珠菌和表皮葡萄球菌的最小抑菌浓度(MIC)分别为0.10,0.05,0.20,0.20,0.20,0.20,0.20,0.10(g/ml);尿路清对解脲支原体和人型支原体的MIC分别为3.91g/L和7.81g/L。结论:中医药在泌尿生殖道感染的治疗上具有重要作用。

Obyective:To understand the antibacterial activity of Niaoluqing (NLQ), a kind of Chinese medicinal herbs liquid , ageinst common pathogenic bacteria in urinary and genital system. Methods: Tthe inhibitory effect of NLQ on international standard strain of UU(T8 )and MH was examined with microdilution method. MH were cultured in a liquid medium in which NLQ was added in doubling dilution, and The antibacterial activity of NLQ against other germs always found in urnary and genital system was examined with fluid tube culture method. Results; NLQ had a high sensitivity to UU( MIC = 3. 91g/L) ,a low sensitivity to MH(MIC =7. 81g/L) ,and a high sensitivity to Staphylococcus aureus,beta Streptococcus, Catarrhalis,Escherichia coli,Pseudomonas,Aeruginosa, Candida albicans and Staphyliciaus epidermidis. Conclusion; Chinese medicinal herbs liquid are of momentous roles in the treatnent of UU, MH and other pathogenic germs infection. It was suggested that the necessary work should be strengthened in the field of experimental or foundmental research of the diseases.