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耳针和六味地黄加味对实验性骨质疏松症的影响 被引量:5

Effect of ear-acupuncture and plus flavor Liuweidihuang pill on laboratory osteoporosis
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摘要 目的 :探讨耳针和六味地黄加味对去势雌鼠骨质疏松症的影响。方法 :通过切除 6月龄雌鼠双侧卵巢建立骨质疏松症的动物模型。大鼠被随机分为 6组 ,各组分别经耳针、六味地黄加味和苯甲酸雌二醇的 3个月治疗后将大鼠处死、取血 ,用放免法测定血清 E2 ,BGP,IL-1,IL-6和骨 BMD,BMC含量。结果 :耳针、六味地黄加味和苯甲酸雌二醇的治疗均能提高 E2 ,BMD,BMC的水平 ,同时能抑制 BGP,IL-1,IL-6的分泌。结论 :耳针、六味地黄加味对骨质疏松症的骨形成和骨吸收有调节作用 ,能早期预防和治疗骨质疏松症 ,是值得进一步研究的新方法。 Objective: It is to observe the effects of ear acupuncture (EA) and plus flavor Liuweidihuang pill (PFLP) on osteoporosis of ovariotomy female rats. Methods: Osteoporosis model was established by excising both sides ovary of 6 month old female rats. The rats were randomly divided into six groups. The groups were treated respectively with EA, PFLP and estradiol for three months. Then the rats were sacrificed and their blood was collected. The E 2, BGP, IL 1, IL 6 of serum and BMD, BMC of bone were tested by RIA. Results: The EA, PFLP and estradiol could increase the levels of E 2, BMD, and BMC and inhibit the secretion of BGP, IL 1, and IL 6. Conclusion: EA and PFLP have adjustable effects on the bone formation and the bone absorption of osteoporosis, and can prevent earlier period and treat the osteoporosis. They are worth to further research as a new method.
出处 《现代中西医结合杂志》 CAS 2002年第10期902-904,共3页 Modern Journal of Integrated Traditional Chinese and Western Medicine
基金 贵州省教委基金课题 (F99- 1 )
关键词 耳针 不地黄加味 大鼠 骨质疏松 骨形成 骨吸收 中医药疗法 EA PFLP rat osteoporosis bone formation bone absorption
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