治疗原发性高血压症3种药物治疗方案的成本——效果分析

Cost-effectiveness analysis of three different drugs for essential hypertension.

目的 :探讨不同药物治疗原发性高血压症的经济效果。方法 :选择 10 6例原发性高血压症 (临床诊断 1- 2级 )、无严重心、脑、肾并发症患者 ,用 3种不同的药物治疗 ,分为A组 :卡托普利 +西之达 +银杏叶 (38例 )、B组 :倍他乐克 +西之达 +银杏叶 (33例 )、C组 :波依定 +西之达 +银杏叶 (35例 ) 3组 ,均为口服给药、疗程 10wk。运用药物经济学的成本———效果分析方法进行评价。结果 :3种治疗方案的总成本依次为35 96 5 0、36 71 90、3885 4 0元 ,其总有效率分别为 86 84 %、90 91%、97 14 %。结论 :B方案为最佳治疗方案。

OBJECTIVE:To evaluate the economic effectiveness of different therapeutic regimens for essential hypertension.METHODS:106 patients with first and second phase hypertension and without serious heart,brain and kidney complication were divided into 3 groups.Each group was given different drugs,Agroup:captopril+simvastatin+instructions(38cases),Bgroup:betaloc+simvastatin+instructions(33cases),Cgroup:plendil+simvastatin+instructions(35cases).All the drugs were taken orally.The treatment time was 10wk.RESULTS:The costs of A,B,C regimens were RMB 3596.50?3671 90?3885 40 Yuans and the effective rates were 86.84%?90 91%?97 14%,respectively.CONCLCUSION:According to the results of cost-effectiveness analysis,Bgroup:is the best choice among the three therapeutic regimens.