糙叶败酱活性成分的研究

Studies on Immunocompetent Constituents of Patrinia scabra Bunge

采用硅胶柱层析技术从中药糙叶败酱(Patrinia scabra Bunge)的根中分离得到了5个化合物,经理化常数测定和波谱分析,鉴定其分别为落叶松脂醇(Ⅰ)、丁香树脂醇(Ⅱ)、东莨菪内酯(Ⅲ)、槲皮素(Ⅳ)、阿魏酸(Ⅴ)。所有化合物均首次从该植物中分得。

Five compounds were isolated from the roots of Patrinia scabra Bunge separated and purified on sillica gel column chromatog-raphy. Their structures were elucidated on the physico-chemical propeties and spectral data as lariciresinol (Ⅰ), syringaresinol (Ⅱ), scopo-letin (Ⅲ) .quercetin (Ⅳ) , ferulaic acid (Ⅴ) . All componds were obtained from P. scabra for the first time. In vitro bilogical test of these compounds showed that syringaresinol was able to stimulate T and B lymhocyte proliferation.