摘要
目的了解不同时期医院感染中ESBLs的改变及对抗生素敏感性的影响 ,对产ESBLs菌医院感染病例进行危险因素相关关系分析。方法双纸片协同试验检测ESBLs,对不同时期产ES BLs菌的耐药性进行比较 ,并对相关病例进行调查。结果感染终末期耐药率与初期比较差异有显著意义 ;医院感染中发生酶改变占观察病例的 5 3 6 %。结论住院时期长、不合理使用抗生素与耐药菌株形成是医院感染的直接危险因素。
Objective To investigate the alteration of sensitivity of EBSLs on antibiotics in hospital infection in different phase and explore the related dangerous factors. Methods ESBLs were detected by Double-disk Synergy Tests. The drug-resistances of ESBLs-producing bacteria in different phase were compared.Results The rate of drug-resistance of the infectious final-phase was significant different from that of initial stage. The enzyme alteration in hospital infection is 53% in observed cases. Conclusion The direct dangerous factors of hospital infection are in hospital for too long time, irrationally using antibiotics and the drug-resistance bacteria formed.
出处
《贵州医药》
CAS
2002年第5期407-408,共2页
Guizhou Medical Journal
