摘要
Clara细胞是衬覆于远端细支气管的非纤毛上皮细胞 ,具有非粘液非浆液性分泌特性。已证实Clara细胞具有分泌、生物转化、前体细胞作用、离子主动转运等多种功能 ,在器官保护、气道上皮更新和损伤修复。
出处
《国外医学(生理病理科学与临床分册)》
2002年第2期139-141,共3页
Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
参考文献20
-
1Lopper CG, Hyde DM, Buckpitt AR, et al. In Crystal RG, West JB,ed. The Lung: Scientific foundations[J]. Philadelphia; Loppincott-Roven Publishers, 1997:517 - 533.
-
2Boers JE, Ambergen AW, Thunnissen BJM. Number and proliferation of Clara cells in normal human airway epithelium [ J ]. Am J Respir Crit Care Med, 1999,159:1585 - 1591.
-
3Singh G, Katyal S. Clara cell proteins[J]. Ann NY Acad Sci, 2000,923:43-58.
-
4Chang A, Ramsay P, Zhao B, et al. Phsyiological regulation of ureroglobin/CCSP expression[J]. Ann NY Acad Sci, 2000,923:181-192.
-
5Stripp BR, Reyolds SD, Plopper CG, et al. Pulmonary phenotype of CCSP/UG deficient mice: A consequence of CCSP deficiency or alltered Clara cell function[J]. Ann NY Acad Sci, 2000,923:202-209.
-
6Hayashida S, Harrod KS, Whitsett JA. Regulation and function of CCSP during pulmonary Pseudomonas aeruginosa infection in vivo[J]. Am J Physiol, 2000,279:L452 - L459.
-
7Harrod KS, Mounday AD, Stripp BR, et al. Clara cell secretory protein decreases lung inflammation after acute virus infection[J]. Am J Physiol, 1998,275:L924- L930.
-
8岳少杰,罗自强.肺表面活性物质结合蛋白的生理功能[J].国外医学(呼吸系统分册),1995,15(2):79-82. 被引量:5
-
9Hohlfeld J, Fabel H, Hamm H. The role of pulmonary surfactant in obstructive airways disease[J]. Eurp Respir J, 1997,10:482-491.
-
10Singh G, Katyal SL. Clara cells and Clara cell 10 kD protein(CC10)[J]. Am J Respir Cell Mol Biol, 1997,17:141 - 143.
共引文献4
-
1施爱民,王心如.支气管肺泡灌洗液成份分析与肺毒理学研究概况[J].中国职业医学,2000,27(2):46-47. 被引量:9
-
2杨琳琳,封志纯.肺表面活性物质蛋白B、C的提纯及生物活性功能分析[J].中国优生与遗传杂志,2001,9(3):26-27.
-
3李贤,黄中新.肺泡的发育与新生儿肺透明膜病[J].四川解剖学杂志,2002,10(1):21-25. 被引量:1
-
4史志澄.肺表面活性物质与环境-职业性疾病[J].中华劳动卫生职业病杂志,2002,20(2):155-157. 被引量:2
同被引文献17
-
1温志红,农光民.Clara细胞、Clara细胞分泌蛋白在哮喘发病机制中的作用[J].医学综述,2006,12(13):769-770. 被引量:3
-
2Heng Wang,Xiang Lu,Ping-Ping Cao,et al.Histological and immunological observations of bacterial and allergic chronic rhinosinusitis in the mouse[J].Am J Rhinol,2008,22:343.
-
3Robert Po Schleimer,Atsnshi Kato,Robert Kern,et al.Epithelium:At the interface of innate and adaptive immune responses[J].J Allergy Clin Immunol,2007,120:1279.
-
4Paola D.Vermeer,James Denker,Miriam Estin,et al.MMP-9 modulates tight junction integrity and cell viability in human airway epithelia[J,] ,Am J Physiol Lung Cell Mol Physiol,2009,296:L751.
-
5Shinji Okada,Hirohito Kita,Terry J.George,et al.Migration of Eosinophils through Basement Membrane Components In Vitro:Role of Matrix Metalloproteinase-9[J].Am J Respir Cell Mol Biol,1997,17:519.
-
6M Benson,M Fransson,T Martinsson,et al.Inverse relation between nasal fluid Clara Cell Protein 16 levels andsymptoms and signs of rhinifis in allergen-challengod patients withintermittent allergic rhinitis[J].Allergy,2007,62:178.
-
7TAE-BIN WON,SONG-HUA QUAN,CHAE-SEO RHEE,et al.Expression of uteroglobin in a murine model of allergic rhinitis[J].Acta Oto-Laryngologica,2007,558:83.
-
8杨远,林勇,黄静.CpG ODN和地塞米松对哮喘气道的重塑及MMP-9、TIMP-1表达的影响[J].中国病理生理杂志,2007,23(10):1977-1981. 被引量:8
-
9王恒,刘争,陆翔,游学俊,高起学,崔永华.Clara细胞10-KDa蛋白在小鼠细菌性慢性鼻-鼻窦炎模型中的表达[J].临床耳鼻咽喉头颈外科杂志,2008,22(20):937-940. 被引量:3
-
10姚咏明,于燕,吴叶,施志国,盛志勇.The role of gut as acytokine-generating organ in remote organ dysfunction after intestinal ischemia and reperfusion[J].Chinese Medical Journal,1998(6):34-38. 被引量:26
引证文献2
-
1王水斌,王显红,陈卫民,毕蓓,吴立连.MMP-9和CC10在小鼠变应性鼻炎中的表达和相关性研究[J].咸宁学院学报(医学版),2010,24(5):377-381.
-
2裴万敏,孔高茵,李李.克拉拉细胞分泌蛋白减轻兔肺缺血再灌注损伤的炎性反应[J].中国医师杂志,2014,16(8):1117-1119.
-
1武继祥,王启民.低氧条件下豚鼠肺Clara细胞超微结构的观察和定量分析[J].第三军医大学学报,1990,12(6):484-487. 被引量:1
-
2罗佛全,傅华群.内毒素血症大鼠Clara细胞数量和形态学变化[J].江西医学院学报,2006,46(6):9-11. 被引量:2
-
3黄元乔,黄元汛.人体中的钾和钠[J].湖北第二师范学院学报,1994,0(4):55-57.
-
4陈林,张琪.脓毒症中细胞自噬的研究现状[J].中国小儿急救医学,2016,23(11):780-783.
-
5罗凤鸣,王曾礼,刘小菁,刘春涛,章小红,王文志.大鼠哮喘模型Clara细胞及其分泌蛋白的表达[J].中华内科杂志,2003,42(7):466-469. 被引量:9
-
6汤秀英,何冰,迟春花,谢燕玲,柴立军.实验性慢性阻塞性肺疾病肺Clara细胞的超微结构变化[J].电子显微学报,2002,21(4):377-379. 被引量:1
-
7李青,蔡立勉.血管活性肠肽(VIP):抗炎与器官保护的实验研究进展[J].中国医疗前沿,2007,2(12):66-67. 被引量:3
-
8罗自强,岳少杰,赵必红.Clara细胞分泌蛋白[J].生理科学进展,2003,34(3):227-230. 被引量:8
-
9刘芳,徐启勇,叶燕青.肝细胞生长因子与器官保护[J].国际呼吸杂志,2005,25(S1):63-65. 被引量:1
-
10杨雪,曾思,兰志勋.p38丝裂原活化蛋白激酶信号通路在丙泊酚器官保护中的作用[J].医学综述,2015,21(6):961-964. 被引量:1