摘要
目的 :观察石杉碱甲治疗多梗死性痴呆 (MID)的临床疗效。方法 :2 0例MID患者均口服石杉碱甲 15 0μg ,bid ,连服 6周为 1个疗程。 结果 :治疗后患者认知功能MMSE评分 ( 15 .92± 5 .9)分 ,较治疗前 ( 10 .98± 4.9)分显著提高 (P <0 .0 5 ) ,认知功能改善的总有效率 70 .0 % ,其中显效率 2 5 .0 % ,有效率 45 .0 %。结论 :石杉碱甲对MID患者的认知功能障碍有一定的改善作用。
Objective:To survey the therapeutic effect of huperzine A in the treatment of patients with multi infarct dementia (MID). Methods:20 patients with MID were given each po 150 mg of huperzine A b.i,d. in a course of 6 consecutive weeks. Results:The mean MMSE score was significantly increased after the treatment (15.92±5.9) as compared with that before the treatment(10.98±4.9)(P<0.05). The total effective rate was 70.0%, while the therapeutic effects in 25.0% of the patients were scored as excellent. Conclusion:Huperzine A has a fair therapeutic effect on the cognitive function in patients with MID.
出处
《医药导报》
CAS
2002年第5期275-276,共2页
Herald of Medicine
关键词
石杉碱甲
痴呆
多梗死性
认知功能
Huperzine A
Multi infarct dementia
Cognitive function
