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特应性皮炎病因及发病机制的研究进展 被引量:11

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摘要 特应性皮炎是一种血清IgE增高、常伴发哮喘和过敏性鼻炎的慢性、复发性、瘙痒性、炎症性皮肤病。其发病机制较为复杂 ,与遗传、环境、免疫和对生理药理介质反应异常等因素有关。对特应性皮炎发病机制的研究 ,进一步明确与其发病机理直接相关的效应细胞及效应分子 ,包括局部细胞因子的释放、辅助T细胞的分化、IgE的多种效应、感染因素以及超抗原等 ,以及深入了解它们在特应性皮炎炎症过程中的作用 。
作者 王鹰 刁庆春
出处 《国外医学(皮肤性病学分册)》 2002年第3期154-157,共4页 Foreign Medical Sciences(Section of Dermatology and Venereology)
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  • 1Leung DY.Atopic dermatitis:new insights and opportunities for therapeutic intervention.J Allergy Clin Immunol 2000.105(5):860-876.
  • 2Laughter D.Istvan JA,Tofte SJ.et al.The prevalence of atopic dermatitis in Oregon schoolchildren.J Am Acad Dermatol.2000.43(4):649-655.
  • 3Kagi MK,Wuthrich B.Montano E.et al.Differential cytlkine profiles in peripheral blood lymphocyte supematants and skin biopsies from patients with different forms of atopic dermatitis.psoriasis and normal individuals.Int Arch Allergy Immunol,1994,103(4):332-340.
  • 4Hamid Q.Naseer T.Minshall EM.et al In vivo expression of IL-12 and IL-13 in atopic dermatitis-J Allergy Clin Immunol.1996.98(1):225-231.
  • 5Laberge S.Chaffar O.Boguniew icz M,et al.Association of increased CD4+ T-cell infiltration with increased IL-16 gene expression in atopic dermatitis.J Allergy Clin Immunol.1998.102(4 Pt 1):645-650.
  • 6Bratton DL.Hamid Q.Boguniewicz M,et al.Granulocyte macrophage colony-stimulating factor contributes to enhanced monocyte survival in chronic aropic dermaritis.J Clin Invest.1995.95(1):211-218.
  • 7Forrest S.Dunn K.Elliott K,et al.Identifying genes predisposing to atopic eczema.J Allergy Clin Immunol.1999.104(5):1066-1070.
  • 8Chan SC,Brown MA,Willcox TM.et al.Abnormal IL4 gene xpression by atopic dermatitis T lymphocytes is reflected in altered nuclear protein interactions with IL4 transcriptional regulatory element.J Invest Dermatol 1996.106(5):1131-1136.
  • 9Jirapongsanamuruk O,Hofer MF.Trumble AE.et al.Enhanced expression of B7.2(CD86)in patients with atopic dermatitis:a potential role in the modulation of IgE syntbesis.J Immunol.1998.160(9):4622-4627.
  • 10Rattis FM.Peguet-Navano J.Staquet MJ.et al.Expression and function of B7-1 (CD80)and B7-2 (CD86) on human epidermal Langerhans cells Eur J Immunol.1996.26(2):449-453.

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