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CXCR3及其配体与皮肤病 被引量：4

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摘要 趋化因子作为具有多种生物活性的多肽受到重视。本文回顾了CXC趋化因子受体 3及其配体γ干扰素诱导性肽 10、γ干扰素诱导性单核细胞因子和γ干扰素诱导性T细胞α化学趋化因子的结构、它们之间相互作用、生物学功能、受体活化后细胞内信号传导途径以及它们与变态反应性皮肤病、银屑病。
作者 刘伦飞 郑敏
机构地区 浙江大学医学院附属第二医院皮肤科
出处 《国外医学（皮肤性病学分册）》 2002年第3期166-169,共4页 Foreign Medical Sciences(Section of Dermatology and Venereology)
关键词 CXC趋化因子 受体 皮肤病 变态反应性皮肤病 银屑病
分类号 R751.02 [医药卫生—皮肤病学与性病学]
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参考文献26

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同被引文献24

  • 1刘海娜,吴春玲,蒋莉,张晓莉,李舒帆,王晓非.系统性红斑狼疮患者血浆巨噬细胞衍生趋化因子水平及临床意义[J].中华风湿病学杂志,2005,9(3):142-144. 被引量：8
  • 2Kakinuma T, Wakugawa M, Nakamura K et al. High level of thymus and activation-regulatedchemokine in blister fluid and sera of patients with bullous pemphigoid[J]. Br J Dermatol,2003; 148(2) :203-210.
  • 3Flier J, Boorsnm D M, Bruyrmeel D Pet al. The CXCR3 activating chemokines IP-10, Mig and IP-9 are expressed in allergic but not in irritant patch test reactions [ J ]. J Invest Dermatol, 1999 ; 113 (4) : 574-578.
  • 4Ono S J, Nakamura T, Miyazaki D et al. Chemokines: roles in leukocyte development, trafficking, and effector function[J]. J Allergy Clin Immunol, 2003 ; 111 (6) : 1185-1199.
  • 5Ruehhnmm J M, Xiang R, Niethammer A Get al. Mig/CXCL9 chemokine gene therapy combines with antibody eytokine fusion protein to suppress growth and dissemination of murine colon carcinoma[J].Cancer Research, 2001 ;61(23) :8498-8503.
  • 6Horikawa T, Nakaymna T, Hikita I et al. IFN-gamma-inducible expression of thymus and activation-regulated chemokine/CCL17 and macrophage-derived chemokine/ CCL22 in epidermal keratinocytes and their roles in atopic dermatitis [ J ]. hat Immunol, 2002 ; 14 (7) : 767-773.
  • 7Hashimoto S, Nakamura K, Oyama N et al. Macrophage-derived chemokine (MDC)/CCL22 produced by monocyte derived dendritic cells reflects the disease activity in patients with atopic dermatitis[ J ]. J Dermatol Sci, 2006; 44(2) :93-99.
  • 8Xiao T, Fujita H, Saeki H et al. Thymus and activation-regulated chemokine(TARC/CCLl7) prcduced by mouse epidermal Langerhans cells is upregulated by TNF-alpha and IL-4 and downregulated by IFN- gamma [ J ]. Cytokine, 2003 ; 23 ( 4-5 ) :126-132.
  • 9Spandau U,Toksoy A,Goebeler M,et al.MIG is a dominant lymphocyte-attractant chemokine in lichen planus lesions.J Invest Deimatol,1998,111(6):1003-1009.
  • 10Flier J,Boorsma DM,van Beek PJ,et al.Differential expression of CXCR3 targeting chemokines CXCL10,CXCL9,and CXCL11 in different types of skin inflammation.J Pathol,2001,194(4):398405.

引证文献4

二级引证文献12

国外医学（皮肤性病学分册）
2002年 第3期

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