^(13)C-尿素呼气试验检测胃癌患者幽门螺杆菌感染的结果分析

Analysis of the result of ^(13) C-urea breath test in detection of Helicobacter pylori infection in gastric cancer patients

目的 :13 C 尿素呼气试验 (13 C UBT)检测幽门螺杆菌 (HP)感染并探讨与胃癌的关系。方法 :术前3天及手术后 10天对 5 3例胃癌病人进行13 C UBT检测并与 36例健康人群对照 ,以探讨胃癌病人HP的感染率。结果 :HP感染率健康对照组为 0 ,早期胃癌组为 75 .0 % ,中晚期胃癌组为 6 5 .8% (P <0 .0 5 )。结论 :HP感染是胃癌发生序列过程中的重要触发因子 ,在早期胃癌的发生中起重要作用。

Objective:To study the relationship between detection of Helicobacter pylori(H.pylori)infection with 13 C urea breath test( 13 C UBT)and gastric cancer.Methods: 13 C UBT were carried out in 53 cases of gastric cancer patients at 3 days before operation and 10 days after operation.Thirty six healthy individuals were detected as normal control.The rate of H.pylori infection in gastric cancer patients was calculated and compared.Results:The rate of H.pylori infection of the healthy control group was 0,but that of the early or advanced gastric cancer groups were 75% and 65.8% respectively (P<0.05).Conclusion:H.pylori infection is an important trigger factor in the sequence of occurrence of gastric cancer,and it is very important in the development of early gastric cancer.