摘要
目的 :评价急性心肌梗死 (AMI)延迟经皮冠状腔内成形术 (PTCA)及支架植入术对心肌灌注及左心室功能的近期疗效。方法 :初次 AMI患者 56例分为 PTCA及支架植入组 (治疗组 ) (n=30 )和对照组 (n=2 6)。治疗组在 AMI后1 5~ 30 d行延迟 PTCA治疗。治疗组术前 1~ 3天、对照组 AMI后第 1 5~ 30天行第 1次单光子发射计算机断层及心脏超声检查 ,该检查后 1月、6月各复查 1次。结果 :治疗组术后 1月、6月梗死区域的缺血程度均较术前有明显好转(P<0 .0 1 ) ;术后差别无显著性 (P>0 .0 5)。对照组第 2、3次检查均较第 1次有明显好转 (P<0 .0 1 )。治疗组较对照组改善更为明显 (P<0 .0 1 )。 1月、6月后治疗组在射血分数、左室扩大和室壁运动异常积分同对照组相比 ,改善明显 (P<0 .0 1 )。在室壁瘤发生上 ,并无明显差别 (P>0 .0 5)。结论 :表明 AMI患者梗死后梗死区域内尚有存活心肌 ,延迟PTCA及支架植入能使梗死区内更多的心肌存活。 AMI发病后积极进行延迟 PTCA及支架植入治疗 。
Objective:To assess the short term effects of delayed percutaneous transluminal coronary angioplasty (PTCA) and implanting intracoronary stents on myocardial perfusion and left ventricular function in patients with acute myocardial infarction (AMI).Methods:56 patients with AMI were divided into delayed PTCA +stent group (treatment group) and control group.The treatment group were received delayed PTCA and coronary artery stents after AMI 15~30 days.The first examination of 99 Tc MIBI and two dimensional echocardiography was performed before PTCA +stent 1~3d ays (treatment group) and after AMI 15~30 days (control group).And followed the second examination (1 month later),the third (6 months later).Results:One month and half year after procedure (PTCA +stent),the blood flow deficit degree of myocardial infarction area in treatment group was better improved.But there were no significant difference in post procerdure (one month later and six month later ( P >0.05).So were the ventricular wall motion abnormality scores,left ventricular diatation and left ventricular ejction fraction (LVEF) ( P <0 01).And there were no significant difference in the left ventricular aneurysms ( P >0.05).Conclusion:There are residual myocardial viability in the AMI regions and PTCA+stent keeps more joepardized myocardial viable.Active therapy after AMI can significantly improve left ventricular function and myocardial perfusion.
出处
《华夏医学》
2002年第2期149-151,共3页
Acta Medicinae Sinica
关键词
急性心肌梗死
PTCA
支架
单光子
心肌灌注
左室功能
二维超声心动图
acute myocardial infarction
delayed percutaneous transluminal coronary angioplasty
coronary artery stents
single photon
left ventricular function
myocardial perfusion
two dimensional echocardiography