老年高血压左室肥厚逆转与QT离散度及室性心律失常的关系

The relationships between Q-T dispersion and ventricular arrhythmia and the reversal of older hypertensive left ventricular hypertrophy

目的 :探讨老年高血压左室肥厚患者在LVH逆转与QT离散度 (QTd)及室性心律失常 (VA)的关系。方法 :90例老年高血压LVH患者在服用降压药物治疗前、治疗后 3个月、6个月行超声心动图、ECG及Holter检查 ,比较LVH逆转前后QTd的改变及VA的发生情况。结果 :①治疗后 3个月 ,LVH即有明显逆转 ,6个月时LVH逆转更明显 ,LVMI较治疗前明显降低 ,P<0 0 1。②QTd也随LVH逆转而缩短 ,治疗后与治疗前比较有明显差异 ,P <0 0 1。③VA及复杂性VA的发生率明显下降 ,P<0 0 1。结论 :老年高血压LVH患者经持续降压治疗 ,LVH逆转 ,QTd改善 。

Objective:To detect the relationship between Q-T dispersion and ventricular arrhythmia and the reversal of older hypertensive left ventricular hypertrophy.Methods:Echocardiogram,cardiogram and Holter were examined before and after three and six months in administration of antihypertensive medicines in 90 cases older hypertensive left ventricular hypertrophy,the change of QT dispersion and the incidence of vantricular arrhythmias during the reveral of LVH were compared.Results:①Three months after treatment,the reversal of LVH were significant,after six months the reversal of LVH were more significant,LVMI significantly decreased than before(P<0 01).②The QTd were shorter than before(P<0 01).③The incidence of vantricular arrhythmia significantly decreased(P<0 01).Conclusion:Persistent antihypertensive therapy could improve LVH and QTd,and decrease the incidence of ventricular arrhythmias.