550例支原体药敏结果分析

RESULTS ANALYSIS ON DRUG RESISTANCE OF MYCOPLASMA IN 550 PATIENTS WITH MYCOPLASMA INFECTION

目的 :了解本地区感染泌尿生殖系的解脲、人型支原体耐药情况。方法 :对性病科和妇科门诊近3年来 5 5 0例支原体感染者用支原体药敏试剂盒进行司巴沙星 (SPA)、克拉霉素 (CL A)、可乐必妥 (CRA )、交沙霉素 (JOS)、阿奇霉素 (AZI)、罗红霉素 (ROX)、强力霉素 (DOX)、美满霉素 (MIN)、氧氟沙星 (ODL)、乙酰螺旋霉素 (ASP)、四环素 (TET)、红霉素 (ERY) 12种抗生素的药敏试验。结果 :统计近 3年耐药率 ,总计依次是 4.2 %、8.4%、10 .4%、2 3.2 %、2 3.8%、2 9.6 %、2 9.6 %、33.0 %、43.1%、5 5 .3%、6 1.9%、82 .7%。结论 :耐药率司巴沙星、克拉霉素、可乐必妥较稳定 ,基本低于 10 % ,其余均较高且大部分呈逐年增长趋势 ,且解脲和人型支原体耐药性有较大差异。

Objective:To understand the Mycoplasma infection and drug resistance of Mycoplasma in patients with the urogenital infection in our district. Method: Mycoplasma IST kits were used in 550 patients with Mycoplasma infection taken from the STD and synopathic clinic in last 3 years. Results: The result showed that the resistance rates of the tested Mycoplasma against Sparfloxacin(SPA),Clarithromycin(CLA),Cravit(CRA),josamycin(JOS),Azithromycin(AZI),Roxithromycin(ROX),deoxytetracycline(DOX),Minocin(MIN) ofloxacin(OFL),acetospiramycin(ASP),(TET),erythromycin(ERY),were 4.2%,8.4%,10.4%,23.2%,23.8%,29.6%,29.6%,33.0%,43.1%,55.3%,61.9%,82.7%,respectively. Conclusion: The resistance rates of the tested Mycoplasma against SPA.CLA.CRA were stable ,the other were severe and there were year-to-year appreciated tendency,and greater drug resistance quality disparity exist between Ureaplasma uralyliam(UU)and Mycoplasma hominis(MH).