肝硬变352例回顾分析

Retrospective analysis of cirrhosis in 352 patients

目的 对我院 1971～ 2 0 0 0年 35 2例肝硬变住院病人进行回顾性分析。方法 本文就肝硬变的早期诊断和死亡原因进行了探讨 ,并对我国部分地区肝硬变的报道与本文进行了比较。结果 肝炎后肝硬变为 6 4 8% ,Child[1] 分类C级病人症状重 ,合并症多 ,预后差。肝硬变主要并发症为上消化道出血 (4 4 % )及肝性脑病 (2 1% )。住院病人病死率 31 3% ,且有下降趋势 (P <0 0 5 )。结论 肝硬变发病高峰年龄 38～ 4 9岁 ,病因各地均以肝炎后肝硬变为首位 ,主要死亡原因是上消化道出血和肝性脑病。

Objective To analyze retrospectively cirrhosis of 352 patients treated in the hospital.Methods The early diagnosis,the cause of death were investigated,and compared with those in other regions in China.Results The proportion of post viral hepatic cirrhosis was 64.8%.According to Child classification the patients in degree C had the most serious symptom and the most complications and the worst prognosis.Complications were upper gastrointestinal bleeding(44%) and hepatic encephalopathy(21%).The overall hospital mortality was 31.3%,and tended to decline(P<0.05).Conclusion The peak ages of the disease was 38～49 years old.In all regions the chief pathogeny was post-viral hepatic cirrhosis.The major causes of death are upper gastrointestinal bleeding and hepatic encephalopathy.