镇痛药临床应用规范性的调研分析

A Survey on Clinical Application of Analgesic Drugs

目的:评估镇痛药在住院病人中的应用情况。方法:以限定日剂量(DDD)和药物利用指数(DUI)为指标,对1999年9月～2000年4月住院病人所用镇痛药处方2149张进行分析。同时统计各类晚期癌症患者病例,调查其住院期间镇痛用药实施“癌症三级止痛阶梯疗法”的情况。结果:镇痛药共8种,用药病人年龄分布为1.25～93岁,平均年龄(49.88±16.50)岁,以40～60岁范围内集中(占45.32％),使用率男性68.96％,女性31.04％,8种药物除吗啡注射液DUI<1以外,其余7种药物DUI>1。病例调查发现,有36.70％的癌症患者实施了三阶梯止痛疗法。结论:医生对住院病人所用8种镇痛药中7种药物的日处方量均大于其DDD,且按照癌症三级止痛阶梯疗法用药的比例有待提高。

Objective: To evaluate the utilization of analgesic drugs in our hospital. Methods: To collect 2149 prescriptions of analgesic drugs from Sept. 1999 to Apr. 2000. DDD and DUI for analgesic drugs were calculated as an indicator of rational drug use. To collect each kind of cancer case on advanced stage and investigate the actualizing of three steps analgesic therapy. Results: 8 kinds of analgesic drugs were used. The higher using frequency group was in 40 - 60 years old. The average age was (49.88 ± 16.50) . The use rate of analgesic drugs on male and female was 68.96% and 31.04% , Respectively. DUI of morphine injection was less than 1, The others were more than 1. 36.70% of cancer sufferers were treated with three steps analgesic therapy. Conclusion: It was more than its DDD value that daily dosage of 7 kinds of analgesic drugs prescribed for inpatients. To use analgesic drugs according to three steps analgesic therapy.