摘要
目的:观察恬尔心治疗全麻术后高血压的临床效果。方法:选择31例全麻术后半小时仍然有高血压而收入ICU治疗的高血压病患者,首剂恬尔心0.2mg/kg,生理盐水稀释到10ml,3min内注射完毕,接着以5～15μg·kg^(-1)min^(-1)的剂量微注泵持续给药,观察给药前后心率、血压、心电图的变化。结果:31例患者首剂注射完毕,血压即出现下降,用药后1min时血压显著降低(P<0.05),2min时血压降低更加明显(P<0.01),15～30min左右血压下降至较理想的水平,30～60min内血压处于相对稳定的水平,心率变化不明显(P均>0.05)。结论:恬尔心治疗全麻术后高血压起效快,降压明显,对心率影响小,无明显不良反应。
Objective: To observe the effect of diltiazem on postoperative hypertension after general anesthesia. Methods: 31 patients were charged into ICU because of hypertension half an hour after general anesthesia. All the patients received diltiazem 0.2mg/kg in 3 minutes as a loading dose and then were continuously infusion by 5-15μg·kg-1·min-1 with microsyringe. HR, BP, ECG were monitored. Results: The blood pressure of all the patients declined just after diltiazem were given, and declined obviously after 1 minutes, declined more obviously after 2 minutes, declined to an ideal level after 15-30minutes and kept a stable level in 30-60 minutes. During the observation HR and ECG didn't change obviously. Conclusions: Diltiazem has good effect on postoperative hypertension.
