摘要
目的:观察海捷亚对老年高血压的治疗作用及对靶器官的影响。方法:40例老年高血压患者口服海捷亚(氯沙坦50mg,氢氯噻嗪12.5mg)1片,每日一次,共8周,治疗前后测血压及行24h动态血压监测(ABPM)。结果:治疗第1周有效率50％,第2周达67.5％,服药4周总有效率达73.3％;谷峰比(T/P)SBP78％、DBP77％;对75.8％患者异常的血压昼夜节律有逆转作用;不良反应轻微,对心率、血钾、尿酸影响较小。结论:海捷亚能快速、平稳控制血压。
Objective: To observe the efficacy of the elderly essential hypertension patients treated with HYZAAR and its effect on the target organs. Methods: 40 cases of elderly patients took HYZAAR (Losar-tan 50mg, Hydeochlotothiazide 12.5mg) 1 piece orally per day for 8 weeks. The blood pressure was measured before and after treatment and 24 hours ambulatory blood pressure monitoring was taken. Results: The therapy efficacy was 50% during the first week and 67. 5% at the second week. The total efficacy was 73.3% after 4weeks treatment. It had reversal effect for the abnormal circadian rhythm of blood pressure of 75.8% patients. The therapy had the advantages of little side effect and low effect of heart rate, blood potassium and uric acid. Conclusions: HYZAAR had the efficacy of controlling blood pressure steadily for 24 hours and reversal effect for the abnormal circadian rhythm of blood pressure day and night.
