云南省鹤庆县中江阿拉禾村居民猝死病因调查

Investigate of the a disease unexpected dead in Heqing A La He

目的 探讨云南省阿拉禾村居民猝死病情的病因。方法 对云南省鹤庆县阿拉禾村居民猝死性发病 ,进行临床流行病学调查及实验室病毒学检验分析。结果 发病点人群贫困 ,健康营养、卫生条件差 ,硒营养水平低 ,多年夏秋季发生猝死病例 ,有一定的发病流行特点。心电图检查异常改变占 18.2 % ,示心肌损伤心电图改变占 12 .4 % ;心肌酶学 3项以上升高占 6 6 .7% ,RT- PCR检测到柯萨奇 B组肠道病毒 RNA阳性率达 6 4 .3% ,双份血清中和抗体测定柯萨奇 B3病毒感染占 2 5 %。结论 阿拉禾村居民猝死病因为柯萨奇

Objective Probe into sudden dead epidemic pathogenesis in Yunnan.Methods Pathogenesis in HeQing A LA HE. Engage in investigate of clinical epidemiology, experiment analytical and virology test.Results The poor crowd health conditions and physique defective nutritions, the locale of a disease come on of selenium(se) nutritions lows. Many years taken place case of sudden dead illness in the summer and autumn, possess fixed epidemic characteristic of a disease come on. abnormal change of electrocardiogram(ECG)inspection 18.2 percent, myocardial damage of ECG 12.4 percent, above three item rising of myocardial enzyme 66.7 percent. Coxsackie virus B (CVB) enteroviruse(EVS) RNA of polymerase Chain Reaction(PCR) lest 64.3 percent. The neutralization antibody test of double serum CVB3 virus infection 25 percent. Conclusions The acute myocarditis of infection CVB, EVS and abrupt dead pathogenesis.