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激素肿瘤标志物在妇科恶性肿瘤应用的新进展

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摘要 尿促性腺激素片段(UGF)为hCG代谢后经尿排出的核心片段,UGF在不同的生理、疾病状态下表达率有所不同,UGF联合CA125、SCCA可应用于卵巢恶性肿瘤、子宫内膜癌、宫颈癌、外阴癌的诊断和病情监测。抑制素(INH)和激活素(ACT)都属于性腺蛋白,为转化生长因子β(TGF-β)相关的超家族成员,两者亚单位表达失衡会导致肿瘤的发生。临床监测INH和ACT在卵巢恶性肿瘤、滋养细胞肿瘤、子宫内膜癌、宫颈癌的诊断、临床预后有着重要意义。
出处 《国外医学(妇产科学分册)》 2002年第2期105-108,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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