无创性诱发早搏后强化作用评定冠心病左心室收缩功能

ASSESSMENT OF NONINVASIVELY INDUCED POSTEX TRASYSTOLIC POTENTIATION ON LEFT VENTRICULAR CONTRACTILITY IN THE PATIENTS WITH CORONARY HEART DISEASE

采用食管心房调搏诱发早搏,结合心阻抗微分图观察冠心病早搏后强化程度。经56例检测结果:在SI=750ms,CI=450ms,PI=850ms时,冠心病组RCdz/dt max为1.70±0.27,RHI为2.26±1.14,ΔQ-Z为-0.89±0.30,三项指标均显著高于可疑冠心病组(依次为1.42±0.11,1.35±0.50,-0.82±0.50)及健康人组(依次为1.23±0.15,1.36±0.18,-0.58±0.28)。表明本法能确切反映左心收缩功能,与国外有创性研究结果一致。本研究为评定心肌收缩性和心功能,提供了一种无创、安全、简便、重复性好的新方法,可取代国外的有创性方法用于临床和研究工作。

By using extrasystolc induced by transesophageal pacing combined with the differential impedance cardiogram, the postextrasystolic poten-tiation of the left ventricle was observed in patient with coronary heart disease ( CHD ) . The results of the examination in 56 cases showed that RCdz/dt max(1.70±0.27), RHI ( 2.26 ±1.14 ) and △QZ(-0.89±0.3) of the CHD group were remarkedly higher than those of the suspected CHD ( 1.42±0.11, 1.85 ± 0.50 and -0.82±0.5, respectively ) and of the normal subjects ( 1.23 ± 0.15, 1.36±0.18 and -0.58±0.28, respectively) at SI = 750ms, CI = 450ms and PI = 850ms intervals. It was found that the method could exactly reflect the contractility of the left ventricle and the results obtained were consistent with thos of the invasive studies abroad. Therefore, the method afforded a non-invasive, safe, simple, reliable and new. way for the assessmant of the myocardial contractility and the cardiac function.