摘要
目的 本实验对龟地散在去卵巢大鼠所致骨质疏松大鼠骨代谢方面的影响进行了探讨。结果 实验显示 ,龟地散能明显降低骨质疏松大鼠尿羟脯氨酸和尿钙含量 (P <0 0 1,P <0 0 5 ) ,并可明显增加血清碱性磷酸酶含量 (P <0 0 1)和骨钙素水平 (P <0 0 5 )。结果还显示 ,龟地散对血清钙水平有显著升高作用 (P <0 0 5 ) ,但对血清磷水平的影响却不明显。
Objective\ To study the effect of Gui Di powder (GDP) on bone metabolism in ovariectomized rats. Results\ Urinary hydroxyproline and calcium levels in the GDP group were significantly lower ( P<0 01,P<0 05) than those in the ovariectomized group (OVX). Serum alkaline phosphatase activity ( P< 0 01) and osteocalcin levels ( P< 0 05) increased in OVX rats. Serum calcium level also increased ( P <0 05) but serum phosphorus level did not change, compared with the OVX group. Conclusion\ GDP is effective in preventing osteoporosis induced by ovary excision.
出处
《中国骨质疏松杂志》
CAS
CSCD
2002年第2期171-172,共2页
Chinese Journal of Osteoporosis
基金
辽宁省教委资助计划项目
关键词
龟地散
骨质疏松
羟脯氨酸
骨钙素
骨代谢
Gui Di powder
\ Osteoporosis
\ Hydroxyproline
\ Osteocalcin
\ Calcium
