126例精神分裂症病人的TCD检测结果

A detective results of transcranial doppler in 126 patients with schizophrenia.

目的 分析精神分裂症的TCD特征。方法 将 12 6例精神分裂症病人分为 19～ 39岁和 40～ 49岁两组 ,并检测病人的脑动脉血流速度 (包括收缩峰血流速度和舒张末期的血流程度 )、脉动指数及阻力指数。结果 19～ 39岁组的TCD阳性率为 77.2 7%,40～ 49岁组为 81.5 5 %。两组差异无显著性 (P >0 .0 5 )。两组MCA的收缩峰血流速度与正常人比较明显降低 ,有非常显著性差异 (P <0 .0 1)。结论 脑动脉供血不足是精神分裂症病人在TCD检测中有意义的表现之一。

Objective To study the feature of transcranial doppler in schizophrenia.Methods 126 cases of schizophrenia were conducted on two groups-19～39 year group and 40～49 year group.They were recorded the systolic flow velocity, enddiastolic flow velocity, pulsatility index and resistance index.Results It was found that the systolic flow velocity of middle cerebral artery(MCA)in schizophrenia showed significant decrease as compared with the normal subject(P< 0.01 ).Conclusion The findings suggest that cerebral hypoperfusion is an significant feature of transcranial doppler in schizophrenia.