STD门诊患者支原体感染情况调查及药敏结果分析

The Survey on Mycoplasma Infection and the Analysis of Drug Susceptibility in Out Patients with STD

目的 了解近年STD门诊患者支原体感染及耐药情况。方法 对 499例STD门诊患者进行了支原体培养 ,并对阳性标本做 10种抗生素药敏试验。采用支原体培养、鉴定、药敏一体化试剂盒进行检测。结果 499例中支原体阳性 117例 ,感染率为 2 3 .4%。解脲支原体 (UU )、人型支原体 (MH)及UU +MH混合感染的阳性率分别为 19.4% (97例 )、1.0 % (5例 )、3 .0 % (15例 )。UU对 10种药物敏感性最高的是交沙霉毒 (99.0 % ) ,其次是阿奇霉素 (95 .9% )。耐药性最高为四环素 (3 0 .9% ) ,其次是强力霉素和美满霉素 (均为 18.6% )。结论 STD门诊支原体感染率高达 2 3 .4% ,主要为UU引起 (占 82 .9% ,97/117) ;交沙霉素是治疗泌尿生殖道UU感染的首选药物。

Objective To determine the mycoplasma infection and the drug resistance in out patients with STD.Methods Mycoplasma culture was carried out with the samples of 499 cases and then the susceptibility of mycoplasma to ten kinds of antimicrobial agents were done on the positive samples.The culture,identification and the drug resistance of mycoplasma were carried out with one complex mycoplasma kit.Results 117 of 499 cases were infected with mycoplasma.The total positive rate was 23.4%.The positive rate of UU,MH and mixed both infection were 19.4%(97 cases),1.0%(5 cases),3.0%(15 cases) respectively.The highest susceptibility rate of UU to ten kinds of antimicrobial agents was Jos(99%),the second was Azi(95.%).The highest resistant rate of UU was Tet(30.9%),the second was Dox(18.6%) and Min (18.6%).Conclusion Mycoplasma infection rate is 23.4% in out patients with STD,major mycoplasma is UU (82.9%,97/117); Jos is the first choice to treat urogenital tract infection of UU.