区域动脉灌注治疗急性坏死性胰腺炎——CT分析

Regional arterial infusion for treatment of acute necrotizing pancreatitis——CT analysis

目的 :区域动脉灌注 (RAI)治疗急性坏死性胰腺炎 (ANP)价值的评估。方法 :15 3例为CT所证实的ANP的病例分为两组 ,RAI治疗组 84例 ,综合治疗对照组 69例。RAI治疗后 1个月内至少复查CT 1次 ,分析动脉灌注前后CT征象的变化及临床表现并且和对照组比较分析。结果 :CT显示胰腺肿胀、胰周渗出、胰腺坏死等主要CT征象 ,RAI组治疗的有效率明显高于对照组 ,并发感染率及病死率分别为 11.90 %及 7.14 %。结论 :RAI是急性胰腺炎的新疗法 ,早期的RAI治疗可降低ANP的并发症及病死率 ,是综合治疗的补充及创新。

Objective:To assess the value of Regional intra arterial infusion(RAI) for treatment of acute necrotizing pancreatits(ANP).Methods:One hundred and fifty three patients with ANP were proven by CT.84 cases with RAI therapy (RAI group),69 cases with combined therapy(contrast group).All of the cases were examined by CT at least one time within one month.Detection was made on the clinical and CT improvement in the two groups before and after of the therapy.Results:After the RAI therapy,CT findings such as pancreatic edema,fluid collection and pancreatic necrosis in the RAI group was odviou improve than that in the control group( P <0.05),RAI group showed mortality and secondary infection were 7.14%,11.90%,respectively.Conclusion:RAI is a new therapy method for ANP.Early RAI therapy of the ANP could reduce the secondary infection and mortality,it is complementarity and innovation for combined treament.