未实施碘盐防治的社区人群甲状腺疾病的调查

The study of thyroid diseases in a community not using iodized salt

目的 研究未实施碘盐防治的社区人群甲状腺疾病的患病率。方法 辽宁省盘山社区110 3名 14周岁以上居民参加甲状腺疾病的普查 ,内容包括填写调查表、接受体格检查、测定血清指标及测定尿碘浓度、进行甲状腺B超检查。结果 盘山社区甲亢与甲低患病率分别为 16 3‰和2 7‰ ;亚临床甲亢与亚临床甲低患病率分别为 37 7‰和 9 1‰ ;甲状腺自身抗体阳性率 10 9% ;B超诊断甲状腺肿大率 2 0 7% ,其中弥漫性甲状腺肿占 16 8% ,结节性甲状腺肿占 3 9%。结论 自身免疫参与碘缺乏地区甲状腺肿的发生 ,而且可能是亚临床甲亢与亚临床甲低的主要病因。

Objective To investigate the prevalence of thyroid diseases in a community which did not use iodized salt Methods The survey was conducted in Panshan, Liaoning Province 1 103 inhabitants aged 14 years or more attended the examinations, which included questionnaire, physical examination and serum analysis Iodine in the urine and thyroid B ultrasound examination were also conducted Results The prevalence of overt hyperthyroidism and hypothyroidism was 16 3‰ and 2 7‰,respectively Subclinical hyperthyroidism and hypothyroidism were detected in 37 2‰ and 9 1‰ of the subjects, respectively Serum autoantibodies to thyroid were detected in 10 9% of the entire population The prevalence of goiter was 20 7% (diffuse goiter 16 8% and nodular goiter 3 9%) Conclusion In the iodine deficient areas, perhaps autoimmununization is not only related to the development of goiter but is also the main cause of subclinical hyperthyroidism and hypothyroidism