薄层色谱法分离鉴别速效伤风胶囊中对乙酰氨基酚、咖啡因、马来酸氯苯那敏和人工牛黄

Identification and isolation of paracetamol, caffeine,chlorphenamine-maleate and calculus-bovis in Suxiao-Shangfeng Jiaonang by TLC

目的 :用薄层色谱法分离鉴别速效伤风胶囊中 4种主要成分。方法 :吸附剂为硅胶GF2 54,展开剂为乙腈 -甲醇 -氯仿 (1∶1∶8)。结果 :Rf值分别为 0 .78(对乙酰氨基酚 ) ,0 .88(咖啡因 ) ,0 .2 4 (马来酸氯苯那敏 ) ,0 .13(人工牛黄 )。结论 :4种成分可以完全分离。

OBJECTIVE To identify and isolate of four main continuents in Suxiao Shangfeng Jiaonang by TLC.METHODS TLC was used with SilicaGel GF 254 plate and developing solution of acetonitrile methanol chlorotorm(1∶1∶8).RESULTS The Rf values were 0.74 (paracetamol), 0.88 (caffeine), 0.24 (chlorphenamine ma leate) and 0.13 (calculus bovis).CONCLUSIONS Four continuents are completetly separateled.