不同对比剂在肝细胞癌患者CT增强扫描中效果比较

Comparison between the effects of 2 contrast medias in CT enhancement scanning for HCC

目的:对国产离子型对比剂泛影葡胺与进口非离子型对比剂优维显在肝细胞癌(HCC)患者螺旋 CT增强扫描中效果比较。方法:对198例HCC患者进行肝脏螺旋CT(SCT)三期增强扫描,其中105例选用60%泛影葡胺(含 I 292 g/L),93例选用优维显(含I300 g/L)。观察 2种对比剂的不良反应及 CT影像质量。结果:泛影葡胺组中有3例(2．9%)出现不良反应,其中轻度2例(1．9%),中度1例(1．0%);优维显组有1 例(1．1%)出现轻度不良反应。2组均无重度不良反应与死亡发生(P＞0．05)。影像质量2组近似。结论:国产离子型对比剂对于无高危因素的人群安全可靠,并可获得质量满意的螺旋CT增强图像,是诊断HCC的有效对比剂。

Aim: To compare the effects of 2 contrast medias, ionic urograpHin and nonionic ultrowist in CT enhanced spiral scanning for diagnosis of hepatocellular carcinoma(HCC). Methods : The livers of 198 HCC cases were scanned by triphasic enhanced spiral CT, 60% urograpHin (292 g/L) were administered in 105 cases and ultravist (300 g/L) in 93 cases. The adverse reaction and the quality of CT image were observed respectively. Results: Three cases had adverse reactions, among which 2 cases were mild (1. 9%) and 1 was moderate severe (1. 0%) in 60% urograpHin group . There was 1 mild adverse reactions (1. 1%) in the Ultravist group . Severe reaction and death did not happen in both groups (P>0. 05). The quality of image between two groups was similar. Conclusions: Ionic contrast media urograpHin made in CHina are safe and reliable for patients without high risk factors and satisfactory spiral CT images can be obtained by using it. UrograpHin is an effective contrast media in enhanced SCT for diagnosing HCC.