期刊文献+

瘦素与胚泡着床

下载PDF
导出
摘要 瘦素(leptin)是近年发现的肥胖基因(ob)编码的肽类激素,主要作用于中枢和外周,调节机体的能量代谢和脂肪贮存。近年研究表明leptin与妊娠和生殖调节有关。早孕蜕膜、绒毛都有leptin受体的表达,滋养层细胞还能合成并分泌leptin,提示leptin与胚泡着床有一定关系。leptin的合成和分泌受甾体激素调节。
作者 李蕾
出处 《国外医学(计划生育分册)》 CAS 2002年第2期88-91,共4页
  • 相关文献

参考文献20

  • 1Alfer J, Muller Schottle F, Classen Linke I, et al. The endometrium as a novel target for leptin: differences in fertility and subfertility. Mol Hum Reprod, 2000, 6(7): 595-601
  • 2Kitawaki J, Alfer J, Muller Schottle F, et al. Expression of leptin receptor in human endometrium and fluctuation during the menstrual cycle. J Clin Endocrinol Metab, 2000, 85(5): 1946-1950
  • 3Matsuoka T, Tahara M, Yokoi T, et al. Tyrosine phosphorylation of STAT3 by leptin through leptin receptor in mouse metaphase 2 stage oocyte. Biochem Biophys Res Commun, 1999, 256(3): 480-484
  • 4Barroso G, Barrionuevo M, Rao P, et al. Vascular endothelial growth factor, nitric oxide, and leptin follicular fluid levels correlate negatively with embryo quality in IVF patients. Fertil Steril, 1999, 72(6): 1024-1026
  • 5Brannian JD, Sehmidt SM, Kreger DO, et al. Baseline non-fasting serum leptin concentration to body mass index ratio is predictive of IVF outcomes. Hum Reprod, 2001, 16(9): 1819-1826
  • 6Atanassova P, Popova L. Leptin expression during the differentiation of subcutaneous adipose cells of human embryos in situ. Cells Tissues Organs, 2000, 166(1): 15-19
  • 7Henson MC, Castracane VD, O'Nell JS, et al. Serum leptin concentratians and expression of leptin transcripts in placental trophoblast with advancing baboon pregnancy. J Clin Endocrinol Metab, 1999, 84(7): 2543-2549
  • 8Teppa RJ, Ness RB, Crombleholme WR, et al. Free leptin is increased in normal pregnancy and further increased in preeclampsia. Metabolism, 2000, 49(8): 1043-1048
  • 9Catalano PM. Pregnancy and lactation in relation to range of acceptable carbohydrate and fat intake. Eur J Clin Nutr, 1999, 53 [Suppl 1]: S124-131; discussion S131-135
  • 10Guibourdenche J, Tarrade A, Laurendeau I, et al. Retinoids stimulate leptin synthesis and secretion in human syncytiotrophoblast. J Clin Endocrinol Metab, 2000, 85(7): 2550-2555

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部