抗DNA酶B滴度测定在风湿性心脏病诊断中的价值

The value of anti-DNase B tittation test in diagnosis of rheumatic heart disease

目的 探讨抗 DNA酶 B检测用于风湿性心脏病诊断的价值。方法 检测 43例风湿性心脏病伴活动性风湿热 ,39例风湿性心脏病不伴风湿热活动和 40例非风湿性心脏病 (对照组 )病人血清的抗 DNA酶 B抗体 ,并进行对比。结果 风湿性心脏病伴活动性风湿热组 ,风湿性心脏病不伴风湿热组和对照组抗 DNA酶 B阳性率分别为81.4% ,2 0 .1%和 5 % ,与对照组比较 ,前两组的 P值分别为 <0 .0 0 1和 <0 .0 5。结论 抗 DNA酶

Objective To assess the value of anti-DNase B titration test in diagnosis of rheumatic heart disease. Methods Anti-DNase B titration in rheumatic heart disease patients with active rheumatic fever(43cases), without rheumatic fever(39) and non-rheumatic heart disease patients(control,40cases) were conducted and compared. Results The anti-DNase B positive rate in rheumatic heart disease patients with active rheumatic fever,without rheumatic fever and control subjects were 81.4%,20.1%,5%,respectively. Comparing with control group,the P values of first two group were <0.001 and<0.05,respectively. Conclusion The anti-DNase B titration test can be used as a marker in diagnosis of rheumatic heart disease with active rheumatic fever.