1[1]Breen D, Bihaari D.Acute renal failure as a part of multiple organ failure: the slippery slope of critical illness. Kidney Int,1998,53(Suppl 66):S252
2[2]Tilney NL, Bailey GL, Morgan AP. Sequential system failure after rupture of abdominal aortic aneurysms: an unsolved problem in postoperative care. Ann Surg, 1973, 178(2):1172
3[3]American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the innovative therapies in sepsis. Crit Care Med,1992,20(6):8642
4[4]Thijs A, Thijs LG. Pathogenesis of renal failure in sepsis. Kidney Int, 1998,53(Suppl 66) : S342
5[5]Groeneveld PHP, Kwappenberg KMC, Langermans JAM, et al. Nitric oxide (NO) production correlates with renal insufficiency and multiple organ dysfunction syndrome in severe sepsis. Intensive Care Med, 1996, 22(11):11972
6[6]Spain DA, Wilson MA, Garrison RN. Nitric oxide synthase inhibition exacerbates sepsis-induced hypoperfusion. Surgery,1994,116(2):3222
7[7]Schwartz D, Mendonce M, Schwartz I, et al. Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats. J Clin Invest ,1997, 100(2): 4392
8[8]Navasa M, Follo A, Filella X, et al. Tumor necrosis factor and interleukin-6 in spontaneous bacterial peritonitis in cirrhosis: relationship with the development of renal impairment and mortality. Hepatology, 1998,27(5): 12272
9[9]Mitaka C, Hirata Y, Yokoyama K, et al. Improvement of renal dysfunction in dogs with endotoxemia by a nonselective endothelin receptor antagonist. Crit Care Med,1999,27(1):1462
10[10]0Foex BA, Quinn JV, Little RA, et al. Differences in eicosanoid and cytokine production between injury/hemorrhage and bacteremic shock in the pig. Shock ,1997,8(4):276
6Semenza GL,Wang GL.A nuclear factor induced by hypoxia via denovo protein,synthesis binds to the human erythropoictin gene hanker at a site required for transcriptional activation.Mol Cell Biol,1992,12:5547-5454.
7Huang LE,Bunn HF.Hypoxia-inducible factor and its biomedical relevance.J Biol Chem,2003,278(22):19575-19578.
8Cheng J,Kang X,Zhang S,et al.SUMO -specific protease 1 is essential for stabilization of HIF-1 alpha during hypoxia.Cell,2007,131 (3):584.
9Lee JW,Bae SH,Jeong JW,et al.Hypoxia-induciblefactor(HIF-1) alpha:its protein stability and biological functions.Exp Mol Med,2004,36(1):1.
10Bernhardt WM,Sehmin R,Rosenberger C,et al.Expression of hypoxia -inducible transcription factors in in developing human and rat kidneys.Kidney Int,2006,69(1):114-122.